MMF 500mg Tablet is an immunosuppressive medication that works by weakening the immune system. It is utilized alongside other drugs to safeguard against organ rejection following kidney, liver, or heart transplants. Organ rejection occurs when the immune system recognizes the transplanted organ as foreign and launches an attack against it.
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Mycophenolate Mofetil belongs to the category of medications known as 'immunosuppressants,' and it is utilized to prevent the rejection of transplanted organs like kidneys, hearts, or livers. In cases of transplant rejection, the recipient's immune system identifies the transplanted organ as foreign and launches an attack. If left untreated, this situation can lead to irreversible damage.
The active ingredient in Mycophenolate Mofetil is 'Mycophenolate mofetil,' which is employed to combat organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. Its action involves inhibiting T and B lymphocytes, which are specialized white blood cells responsible for targeting foreign cells, and it also hampers the production of antibodies. These combined effects suppress the immune response, ensuring the acceptance of the transplanted organ.
Adhere to the prescribed regimen for Mycophenolate Mofetil, as advised by your physician. Dosage frequency will be determined based on your specific medical condition. Common adverse effects of Mycophenolate Mofetil encompass diarrhea, vomiting, decreased white and red blood cell counts, and an elevated risk of infections. If any of these side effects persist or worsen, promptly consult your doctor.
Avoid Mycophenolate Mofetil if you have an allergy to 'mycophenolate mofetil' or any of its components. Additionally, refrain from using it if you are pregnant, planning pregnancy, or not utilizing effective contraception or breastfeeding. The medication can induce birth defects or congenital disabilities in unborn infants. If you are a woman of reproductive potential, take a pregnancy test before using Mycophenolate MofetilL. While on the medication, use reliable contraception. Be cautious of increased skin cancer risk; wear protective clothing and minimize sun exposure. Since Mycophenolate Mofetil suppresses the immune system, it heightens susceptibility to infections. Inform your doctor before blood or sperm donation, and avoid vaccinations as their efficacy may be compromised.
Consumption of alcohol can worsen the condition and increase the risk of side effects.
MMF 500mg Tablet is categorized as unsafe during pregnancy (Category D). It can cause birth defects in the fetus. It is not recommended for use in pregnant women.
MMF 500mg Tablet is not recommended for breastfeeding mothers, as it may be excreted in breast milk. However, if the benefits outweigh the risks, your doctor may prescribe it.
Taking MMF 500mg Tablet may not significantly affect your ability to drive. Consult your doctor for advice based on your health condition.
Use MMF 500mg Tablet with caution if you have kidney disease. Dose adjustments might be necessary.
Use MMF 500mg Tablet with caution if you have liver disease. Dose adjustments might be necessary.
MMF 500mg Tablet 10's contains Mycophenolate Mofetil, classified as an 'immunosuppressant'. It prevents organ transplant rejection by dampening the immune system's response. It does so by restraining the activity of white blood cells, which drive immune reactions. Unlike steroids with enduring side effects, MMF 500mg Tablet is a preferable option.
Mycophenolate Mofetil acts as an immunosuppressant by inhibiting inosine monophosphate dehydrogenase (IMPDH), a key enzyme in guanosine nucleotide synthesis. This disruption in the synthesis of DNA components hampers the proliferation of lymphocytes, exerting cytostatic effects. Furthermore, this medication curbs acute rejection of transplanted kidneys and hearts and reduces antibody generation.
Mycophenolic acid operates by inhibiting inosine monophosphate dehydrogenase, an enzyme essential for purine synthesis in human lymphocytes. This action leads to reversible hindrance of purine production, effectively curbing the proliferation of both T- and B- lymphocytes.
Adult Dosage:
Child Dosage:
Renal Impairment:
Geriatric Population:
Elderly individuals may be more susceptible to adverse events, including infections (such as cytomegalovirus tissue invasive disease), gastrointestinal hemorrhage, and pulmonary edema, compared to younger individuals.
Administration:
Overdose:
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Elevated plasma concentrations occur when combined with aciclovir, valaciclovir, ganciclovir, and valganciclovir. Absorption is diminished when co-administered with colestyramine, magnesium- and aluminum hydroxide-containing products, sevelamer, and other calcium-free phosphate binders. Plasma levels decrease with ciclosporin, metronidazole, quinolones, and rifamycins. Progestin plasma levels and oral contraceptive efficacy may be lowered. Plasma levels rise in conjunction with probenecid. The effectiveness of live vaccines may be compromised.
Avoid during pregnancy and lactation. Contraindicated in individuals with rare hereditary deficiency of hypoxanthine-guanine phosphoribosyltransferase (HGPRT), including conditions like Kelley-Seegmiller or Lesch-Nyhan syndrome.
Mycophenolate Mofetil is contraindicated in pregnancy and during breastfeeding. The safe use of Mycophenolate Mofetil during labor and delivery has not been established.
Mycophenolic Mofetil tablets warrant caution due to the following reasons:
Store at a temperature below 30º C in a cool and dry place. Keep it out of the reach of children and pets.
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